Exercise and Bone Density: A Meta-Analysis
MASSACHUSETTS GENERAL HOSPITAL BOSTON
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Purpose Use the meta-analytic approach to examine the effects of exercise on bone mineral density BMD using individual patient data IPD and to compare these results with summary data from the same studies. Scope The specific aim for this project period was to retrieve IPD from existing exercise training studies dealing with the effects of exercise on BMD. Major findings Of the 76 eligible studies we were able to obtain IPD from 29 38.2. Binary multiple logistic regression analysis revealed a trend suggesting that authors of studies conducted in the United States were less likely to supply IPD when compared with authors who conducted studies in other countries adjusted odds ratio 0.324, 95 confidence interval 0.104 to 1.004 . Only 19.0 of authors from studies conducted in the United States versus 52.9 of authors from other countries provided us with IPD. ResultsSignificance The results suggest moderate success in the acquisition of IPD for this data set. In addition, it appears that greater success can be obtained when IPD for this topic is requested from studies conducted in countries other than the United States.
- Anatomy and Physiology
- Medicine and Medical Research