Accession Number:

ADA415328

Title:

Effects of Androgen Blockade on Cognitive Function and Quality of Life in Men with Prostate Cancer

Descriptive Note:

Annual rept. 7 Jan 2002-6 Jan 2003

Corporate Author:

COLORADO UNIV HEALTH SCIENCES CENTER AURORA CO GRANTS AND CONTRACTS

Personal Author(s):

Report Date:

2003-02-01

Pagination or Media Count:

86.0

Abstract:

The purpose of this project is to examine the nature and severity of cognitive impairments experienced by men undergoing continuous androgen deprivation or intermittent androgen deprivation treatment. The cognitive abilities of androgen deprivation patients will be compared with those of a sample of healthy men. We are undertaking collection of data from three groups 35 men on intermittent androgen deprivation therapy, 35 men on continuous androgen deprivation therapy, and an age- and education-matched sample of 35 healthy cancer-free men. Our major hypothesis is that patients undergoing androgen deprivation therapy will experience impairments in those cognitive abilities reported in the research literature to be related to androgen levels e.g., spatial ability, working memory for visual information. There are as yet no results to report. During this first project year we have begun recruiting androgen-deprivation subjects, but the bulk of the time has been spent in obtaining necessary institutional approvals, which has become a very involved and time- consuming process.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE