Accession Number:

ADA413570

Title:

Signal Transduction Based Mouse Models of Prostate Cancer

Descriptive Note:

Final rept. 10 Dec 2001-9 Dec 2002

Corporate Author:

ALBERT EINSTEIN COLL OF MEDICINE OF (YESHIVA UNIV) BRONX NY

Personal Author(s):

Report Date:

2003-01-01

Pagination or Media Count:

139.0

Abstract:

These studies aimed to create a prostate cancer mouse model consortium. The overall objective of this study is to determine the mechanisms governing prostate cancer genesis and progression thereby leading to a better understanding and treatment for this disease. The studies brought together investigators at distinct institutions Albert Einstein College of Medicine AECOM Memorial Sloan Kettering Cancer Center MSKCC, Beth Israel Deaconess Medical Center- HarvardMassachusetts Institute of Technology Health Sciences and Technology, HMSMIT and UC Davis to develop and share a mouse models engineered through sharing distinct models generated by each program member b software technology that will allow for the simultaneous analysis of histopathology and genetic composition of the emerging murine prostate tumors at the different institutions c software technology for functional clustering of data derived from microarray analysis of tumor samples.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE