Optimized Hyperthermia Treatment of Prostate Cancer Using a Novel Intracavitary Ultrasound Array
Annual rept. 14 Dec 2001-13 Dec 2002
PENNSYLVANIA STATE UNIV UNIVERSITY PARK
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The eventual goal this research is to produce an ultrasound hyperthermia array which will uniformally heat the prostate to clinical temperatures for the treatment of prostate disease. This goal can be achieved by accounting for the physical differences between the prostate gland and surrounding tissue structures. It is therefore possible to design transducer to cause uniform heating within the prostate while causing minimal damage to surrounding tissue. The first year of this three year research project was focused on the initial design of the array based on computer simulations of the ultrasound energy interactions with the prostate and surrounding tissue. Three major areas were examined during this term were a tissue modeling b beam design and optimization, and c hyperthermia array design and fabrication. Specifically, the simulations using the k-space propagation has been implement along with temperature rise determination using the bioheat transfer equation. Construction issue regarding the transducer dicing, matching layers and assemble have been dealt along with design of the final applicator body. To summarize, there are no deviations from the original research plan and this research is progressing on schedule.
- Medicine and Medical Research