Accession Number:

ADA413421

Title:

Chemistry of Oligonucleotibe-Gold Nanoparticle Conjugates

Descriptive Note:

Journal article

Corporate Author:

NORTHWESTERN UNIV EVANSTON IL

Report Date:

2003-03-15

Pagination or Media Count:

5.0

Abstract:

Conjugates prepared by immobilizing thiol-terminated oligonucleotides onto gold nanoparticles from stable colloidal solutions in aqueous media The oligo nucleotides can serve as linkers to organize the gold particles reversibly into three dimensional arrays and the gold particles can function as colorimetric reporters for hybridization of the bound oligomers with target oligonucleotides in solution,

Subject Categories:

  • Organic Chemistry
  • Metallurgy and Metallography
  • Radioactivity, Radioactive Wastes and Fission Products

Distribution Statement:

APPROVED FOR PUBLIC RELEASE