Accession Number:

ADA413341

Title:

Enabling Technologies for Advanced Soft Tissue Modeling

Descriptive Note:

Annual rept. 1 Sep 2001-31 Aug 2002

Corporate Author:

MASSACHUSETTS GENERAL HOSPITAL BOSTON

Personal Author(s):

Report Date:

2002-09-01

Pagination or Media Count:

39.0

Abstract:

Soft tissue properties represent a major and significant unknown in the domain of medical modeling and simulation. This program presents a 4 year research effort in defining tissue characteristics of three distinct organs - liver, spleen, and kidney- in vivo. Over the course of this program, we will use novel methods of tissue interrogation to characterize non-linear behavior during slow deformations, as would commonly be seen during surgical manipulations. We will then develop mathematical models which can be optimized to permit near real-time representations of organ behaviors, including the boundary characteristics of organs in situ. During this first year, we examined the in vivo deformations of porcine liver using two different instruments, and determined close agreement between the methods. We initiated mathematical models of our experimental measurements. We also established an experimental standard to compare different datasets, and to measure accuracy of mathematical models of tissue properties. These data were not previously known.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE