Genetics of Breast Cancer in Blacks
Annual rept. 1 Sep 2001-31 Aug 2002
CHICAGO UNIV IL
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Breast cancer in these young Black women is more virulent, leading to a decrease in the overall survival rates for - -- African Americans diagnosed with breast cancer when compared to Whites. Our studies involve a new approach that involves large numbers of breast cancer patients from Africa and provide the first concerted effort to seriously address the contribution of genetic risk factors to the high incidence and mortality from breast cancer in young Black women. We have developed an efficient mechanism to recruit incident cases of early onset breast cancer, with the goal of enrolling 75-100 new cases per year from Nigeria and 50-75 cases per year in the US. We have used the Chronic Disease Network-- a collaborative framework for the study of international comparisons among black populations to develop this infrastructure and we are now awaiting approval of our clinical protocol by the Human Subject Review Committee. We have finalized the instruments to be used, and completed our training in Nigeria.
- Genetic Engineering and Molecular Biology
- Medicine and Medical Research