Accession Number:

ADA411848

Title:

Pharmacotherapy in Children: From Art to Science (Farmacotherapie bij kinderen: van kunst tot wetenschap)

Descriptive Note:

Corporate Author:

RAND CORP SANTA MONICA CA

Personal Author(s):

Report Date:

2002-06-01

Pagination or Media Count:

124.0

Abstract:

It is generally acknowledged that a substantial proportion of prescriptions for children are written in the absence of sound scientific evidence regarding the effectiveness of the drugs. Recent publications have demonstrated that for many drugs, the majority of prescriptions for children are unlicensed or off-label. Clinical research on children in order to obtain this scientific evidence would be expensive, pose ethical issues, and be complicated involving assessments of dosage level, side effects, and considerations of different age levels. Because research to obtain such evidence for use in the pediatric population is not required for a new pharmaceutical product to be licensed, it is understandable even if regrettable that the manufacturers do not engage in this research.

Subject Categories:

  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE