Preclinical Mouse Models of Neurofibromatosis
Final rept. 1 Oct 2000-30 Sep 2002
CALIFORNIA UNIV SAN FRANCISCO
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This is the final report for a two year award made to a Consortium of investigators who are working together to develop, characterize and utilize strains of mice that accurately model tumors that develop in persons with NF1 and NF2. This Consortium accomplished its primary goal of generating and characterizing mouse models of NF1 and NF2 associated tumors for biologic and preclinical therapeutic trials. A number of novel strains were developed, and shared widely with the research community.
- Genetic Engineering and Molecular Biology
- Medicine and Medical Research