Accession Number:

ADA411598

Title:

Spatiotemporal Dynamics of Pacing in Models of Anatomical Reentry

Descriptive Note:

Conference paper

Corporate Author:

CORNELL UNIV MEDICAL COLL NEW YORK

Personal Author(s):

• Sinha, Sitabhra
• Christini, David J.

Report Date:

2001-10-25

Pagination or Media Count:

5.0

Abstract:

Reentry around non-conducting ventricular scar tissue, which often causes lethal arrhythmias, is typically treated by rapid stimulation from an implantable defibrillator. However the mechanisms of termination success and failure are poorly understood. To elucidate such mechanisms, we studied pacing of anatomical reentry in 1-D and 2-D excitable cardiac media models. Our results suggest that the existence of inhomogeneity in the reentry circuit is essential for pacing termination of tachycardia to be successful. Considering the role of such inhomogeneities may lead to more effective pacing algorithms.

Descriptors:

• *STOPPING
• *TACHYCARDIA
• STIMULATION(PHYSIOLOGY)
• ELECTROPHYSIOLOGY
• ARRHYTHMIA
• VENTRICLES

Subject Categories:

• Medicine and Medical Research
• Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE