Receptors, Afferent Signaling and Central Integration in Compensated and Uncompensated Hemorrhagic Shock
Final technical rept. 1 Jan 1997-31 Dec 2002
IOWA UNIV IOWA CITY
Pagination or Media Count:
An understanding of the central and peripheral mechanisms which regulate sympathetic outflow during acute blood volume loss is critical for developing therapeutic treatments for hemorrhagic shock Insight into the mechanisms by which melanopeptides, LV-HTS, and serotonergic drugs facilitate sympathetic outflow during hemorrhage may lead to the development of pharmacological interventions for hemorrhagic shock. Recent experiments conducted in our laboratory provide important new information about the saluretic effects and mechanisms of 3 potential therapeutic strategies to prevent or reverse phase II shock.
- Medicine and Medical Research