Integrated mFlume Reconstitution System for Biological and Medical Supplies. Integrated MEMS Delivery System for Both Liquid and Reconstituted Drugs
Final rept. 4 Mar 1997-4 Feb 2000
CALIFORNIA UNIV BERKELEY REGENTS OF THE UNIV OF CALIFORNIA
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The overall goal of this project was to develop an integrated mFLUME system for the reconstitution, metering, and delivery of biological and medical supplies. This system would allow for the on-demand reconstitution of a wide range of medical supplies that have been stored in dry form for robustness, convenience, and shelf life. The MEMS system required the development and integration of micro-fluidic control components, including valves, pumps, mixing chambers, and fluid ejection ports, with dry material and solvent reservoirs and on-board electronic control systems. A fully integrated device for the reconstitution of a lyophilized drug was never created. However, under this contract, significant advances were made in the area of MEMS-based fluid control systems, including planar valves, mixers, pumps, and interconnects. In addition, integration of a working microFLUMES device into an injection-molded package was demonstrated under a contract extension. In addition, attention was brought to the MEMS community regarding micro-fluid mechanical processes, including the presence and effects of large momentum and scalar gradients.
- Medical Facilities, Equipment and Supplies
- Fluid Mechanics