Accession Number:

ADA411179

Title:

Joint Symbolic Dynamics Analysis of Heart Rate and Systolic Blood Pressure Interactions in Dilated Cardiomyopathy

Descriptive Note:

Conference paper

Corporate Author:

UNIVERSITY OF APPLIED SCIENCES JENA (GERMANY) FACULTY OF MEDICAL ENGINEERING

Personal Author(s):

Report Date:

2001-10-25

Pagination or Media Count:

5.0

Abstract:

The dilated cardiomyopathy DCM induces important changes in the autonomic control. Measures of heart rate HR variability and systolic blood pressure SP variability are sensitive to those changes. The interactions between HR and SP are rather complex and strongly non-linear. We introduced the joint symbolic dynamics JSD as a new short-term high resolution non-linear analysis method to investigate the complex interactions between HR and SP. Continuous non-invasive 30 minutes blood pressure recordings Portapres of 25 patients with DCM and 27 healthy controls CON were analyzed. HR and SP were extracted from the blood pressure time series on a beat-to-beat basis. Using the concept of JSD, HR and SP dynamics were transformed into a bivariate symbol vector. Subsequently, this symbol vector was transformed into a word series words consisting of three successive symbols and the probability of occurrence of each word type was calculated and compared between both groups. We found significant differences partly p0.01 in six word types between DCM and CON. JSD provides an efficient non-linear presentation of HR and SP interactions that offer rather simple physiological interpretations and seems to be particularly suitable for risk stratification in patients with dilated cardiomyopathy.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research
  • Statistics and Probability

Distribution Statement:

APPROVED FOR PUBLIC RELEASE