Cellular Sensing Devices for Assessing Chemicals
TOKYO INST OF TECH YOKOHAMA (JAPAN)
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Several types of cellular biosensors have been developed for assessing chemicals in which the cell responses to chemicals are transduced to the sensor outputs in various manners. The cell layer is fixed in the vicinity of the signal transducer. As an example assessment of immunomodulating chemicals has been performed with a cellular biosensor based on electrochemical determination of the inducible nitrogen oxide synthase iNOS expression in a macrophage-like cell.