Breast Cancer Screening Using Photonic Technology
Annual rept. 15 Aug 2000-14 Aug 2001
CITY UNIV OF NEW YORK
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The research carried out during the current reporting period involved a time-sliced and spectroscopic two-dimensional 2-D near-infrared transillumination imaging of normal and cancerous in vitro human breast tissue specimens b correlating the results of optical measurements with NMR measurements c derivation of analytical solutions of the polarized photon transport equation that provides a more accurate analytical basis for developing three-dimensional 3-D inverse image reconstruction techniques and d development of forward models and 3-D inverse image reconstruction methods. Images recorded with earlier temporal slices of transmitted light were found to highlight cancerous tissues while those recorded with later slices accentuated normal fibrous tissues. Initial spectroscopic imaging experiments show that the ratio, R of light intensity transmitted through the cancerous tissue to that through the corresponding normal tissue show a wavelength dependent variation that has the potential to be used as a useful parameter for cancer identification. Analytical solutions of the polarized photon transport equation are more complete and enable description of polarized light imaging. Faster and more noise-resistant 3-D image reconstruction schemes are being pursued.
- Medicine and Medical Research