DURIP: Monitoring Low Temperature Physiology in Hibernating Mammals
Final progress rept. 1 Dec 2000-30 Apr 2001
MINNESOTA UNIV SCHOOL OF MEDICINE DULUTH DEPT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY
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We have successfully identified genes controlling the physiological characteristics of hibernation in the thirteen-lined ground squirrel Spermophilus tridecemlineatus. Identification of these specific genetic markers has allowed us to study the function of their gene products under highly controlled conditions of temperature, light and humidity. To accomplish this goal specific instrumentation was purchased with this DURIP grant. Measurements of low-temperature physiology in hibernating mammals under controlled conditions required an environmental chamber that allows us to maintain a variety of ambient temperatures ranging from -5 to 20 degrees centigrade.