Impact on BRCA1/2 Testing on Marital Relationships
Annual rept. 4 May 2000-3 May 2001
FOX CHASE CANCER CENTER PHILADELPHIA PA
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The proposed study is a prospective longitudinal examination of the impact of genetic testing for breast-ovarian cancer susceptibility on the marital relationships of women at risk as well as the impact upon the quality of life of their husbands. This study is a companion proposal to an ongoing, DOD-funded prospective study that is evaluating the outcomes of genetic testing for breast-ovarian cancer susceptibility on individuals from hereditary breast cancer families. The proposed study extends the ongoing DOD-funded study to examine the impact of genetic testing upon the marital relationship and the psychosocial impact on the spouse. Specific aims of the study are 1 to evaluate the short- and long-term impact of BRCA 12 testing on psychological distress both general and cancer-specific of spouses of participants in genetic testing programs 2 to evaluate the short- and long-term impact of BRCA 12 testing on the marital relationships of participants and spouses, and examine whether marital satisfaction is an early predictor of psychological morbidity among participants in genetic testing programs and their spouses 3 to examine the association between spouse responses during the testing process and carriers distress post-notification. Women and their husbands will complete measures of general and cancer-specific distress, marital satisfaction, and marital strain imposed by the testing process.
- Medicine and Medical Research