Accession Number:

ADA386913

Title:

Analysis of Interval Changes on Mammograms for Computer Aided Diagnosis

Descriptive Note:

Annual summary 6 Apr 1999-5 Apr 2000

Corporate Author:

MICHIGAN UNIV ANN ARBOR

Personal Author(s):

Report Date:

2000-05-01

Pagination or Media Count:

50.0

Abstract:

A multistage regional registration technique was developed for identifying masses on temporal pairs of mammograms. In the first stage, an initial fan-shape search region was defined on the prior mammogram. In the second stage, the location of the fan-shape region was refined by warping, based on an affine transformation and simplex optimization. A new refined search region was defined on the prior mammogram. In the third stage a search for the best match between the lesion template from the current mammogram and a structure on the prior mammogram was carried out within the search region. This technique was evaluated on 124 temporal pairs of mammograms containing biopsy-proven masses. Eighty-seven percent of the estimated lesion locations resulted in an area overlap of at least 50 with the true lesion locations. The average distance between the estimated and the true centroid of the lesions on the prior mammogram was 4.215.7 mm. The registration accuracy was improved in comparison with our previous study that used a data set of 74 temporal pairs of mammograms. This improvement gain is mainly from the local affine transformation. This technique can be useful for identification of corresponding lesions on temporal pairs of mammograms.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research
  • Computer Programming and Software

Distribution Statement:

APPROVED FOR PUBLIC RELEASE