Susceptibility of Tissue Cultures of Canine Origin to Viruses
Technical Progress rept.
LOVELACE FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH ALBUQUERQUE NM
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The suitability of tissue cultures of canine origin for isolation of viruses from dogs was studied. Primary cultures of kidney, lung, heart and whole dog embryo, low-passage tracheal cells and a continuous line of epithelial-like cells derived from dog kidney were challenged with Z7 viruses. These included the infectious canine hepatitis virus, two coxsackie A and six coxsackie B viruses, three types of poliovirus, ten ECHO viruses, one adenovirus, the western and eastern strains of equine encephalitis virus, and A and B strains of influenza virus. Although each type of cells supported the growth of one or more viruses as evidenced by the cytopathic effect none of them appeared to be more suitable for virus isolation studies than HeLa and monkey kidney cells.
- Medicine and Medical Research