Accession Number:

ADA383762

Title:

Viruses Isolated from Beagle Dogs Exposed to Aerosols of 90Sr and 144Ce

Descriptive Note:

Technical Progress rept.

Corporate Author:

LOVELACE FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH ALBUQUERQUE NM

Report Date:

1967-10-01

Pagination or Media Count:

28.0

Abstract:

Many isolations of coxsackie viruses B1, B3 and B5 and echovirus 6, related if not identical to human viruses of the same types were made from nose, throat and rectal swabs of Beagle dogs. Six unidentified enteroviruses were also recovered. Except for the echovirus 6 such isolations have not been previously reported. Three groups of Beagles receiving an aerosol which provided an initial body burden of 90 90 144 35 micronCikg Sr, 90 MicronCikg Sr and 140 micronCikg Ce showed no difference in the incidence of coxsackie B viruses from that of controls. However, a significantly greater number of isolations of echovirus 6 and of an unidentified enterovirus were made from controls than from exposed dogs. Low NT antibody titres against coxsackieviruses B3 and B5 were found in some of the serum from the Beagles that were examined. No titres were observed for coxsackievirus B1, echovirus 6 or one of unidentified enterovirus which were the most frequently isolated. There was no correlation between virus isolation and serum titres.

Subject Categories:

  • Biochemistry
  • Biology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE