Accession Number:

ADA383752

Title:

Immune Response to a Secondary Stimulus with Leptospira Canicola and Infectious Canine Hepatitis in Beagles Exposed to SR90

Descriptive Note:

Corporate Author:

LOVELACE FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH ALBUQUERQUE NM

Personal Author(s):

Report Date:

1966-06-01

Pagination or Media Count:

17.0

Abstract:

The secondary immune response to L. canicola and ICH virus was depressed in Beagle dogs which had inhaled particles of Sr90 1-2 days and 7 days before the immune stimulus. The initial body burden was 31-46 microcuries per kilogram The peak titre was reached for both antigens within eleven days in both control and exposed dogs. This amount of exposure did not accelerate the rate of decline of the antibodies, and the animals appeared to have recovered their ability to produce antibodies after five months.

Subject Categories:

  • Biology
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE