DID YOU KNOW? DTIC has over 3.5 million final reports on DoD funded research, development, test, and evaluation activities available to our registered users. Click HERE
to register or log in.
Using Mode of Action of Assess Health Risks From Mixtures of Chemical/Physical Agents
AIR FORCE RESEARCH LAB WRIGHT-PATTERSON AFB OH
Pagination or Media Count:
Mixtures of carcinogenic chemicals are a major problem in ground water and soils on DoD and DOE facilities. While there is frequently data available for interactions between chemicals to judge risks from short term exposures, data that describe how interactions influence the development of cancer are very rare. This is largely because of the high cost associated with conducting complex interaction studies over the lifetime of experimental animals. Therefore, it is important that the limited resources that are available for studying interactions be directed towards the development of general principles that can be applied to wide variety of circumstances. The co-occurrence of chlorinated solvents at DoD and DOE facilities such as trichloroethylene TCE, tetrachloroethylene PERC and carbon tetrachloride CT is a case in point.
APPROVED FOR PUBLIC RELEASE