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Investigation of Seminal Plasma Hypersensitivity Reactions

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Annual rept. 23 Sep 1997-22 Sep 1998 (Revised)

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Gulf War GWVeterans andor their sexual partners have been-experiencing burning, pain and swelling of the urogenital tract after exposure to semen since returning from the Persian Gulf which has been referred to as Burning Semen Syndrome BSS. The objectives of this research project are 1 to identify the prevalence of BSS 2 evaluate GW veterans and their sexual partners with BSS 3 to determine if the underlying mechanisms of BSS is immunologic, infectious andor toxicologic in nature 4 to determine if the onset of BSS is related to chemical andor biologic exposures encountered by GW veterans during their tour of duty in the Persian Gulf and 5 to identify potential treatments for BSS. The second year of this project has concentrated on obtaining completed questionnaires from the GW veteran and their spouse or sexual partner, obtaining screening laboratory tests to exclude an obvious underlying cause for their symptoms i.e., sexually transmitted diseases, establishing the respective prevalence of BSS and localizedsystemic seminal plasma protein hypersensitivity among the GW and civilian populations, obtaining body fluids from GW and civilian couples sera and semen to further investigate immunologic and infectious etiologies for their symptoms and finally, identification of control populations.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

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