Synthesis of Tetraazacrown Ethers Containing Two 8-Hydroxyquinoline Side Arms
BRIGHAM YOUNG UNIV PROVO UT DEPT OF CHEMISTRY AND BIOCHEMISTRY
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Four new tetraazacrown ethers containing two 8-hydroxyquinoline side arms were prepared first by reductive amination of 8-acetoxyquinolin-2-carbaldehyde with the appropriate tetraazacrown ether containing two microring NH functions. The resulting bis8-acetoxy-1-quinolinylmethyl-substituted tetraazacrown ethers were treated with 10 aqueous KOH followed by acid to form the N,N-bis8-hydroxy-2-quinolinylmethyl substituted tetraazacrown ethers.
- Organic Chemistry