Accession Number:

ADA361002

Title:

Inverse Protein Folding.

Descriptive Note:

Final rept. 1 Dec 97-31 May 98

Corporate Author:

CALIFORNIA UNIV SAN FRANCISCO

Personal Author(s):

Report Date:

1998-05-31

Pagination or Media Count:

3.0

Abstract:

We have developed Geocore, a computer algorithm that aims to predict the 3D structures of foldable polymers from their monomer sequences. Our first work was on foundations in simplified models, and-most recently we have completed tests in which we found the method is successful in 18 peptides and small proteins. Our continuing efforts will be to speed it up and extend it to larger proteins.

Subject Categories:

  • Biochemistry
  • Polymer Chemistry
  • Computer Programming and Software

Distribution Statement:

APPROVED FOR PUBLIC RELEASE