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A Study of Ultrasonic Wavefront Distortion Compensation.

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Final rept. 1 Sep 94-31 Aug 98

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The first objective of this research is to develop wavefront distortion compensation algorithms to improve spatial and contrast resolution of ultrasound imaging in the detection of breast lesions. The limiting factor for high resolution breast imaging is the acoustic wavefront distortion which is developed as coherent waves propagate inside the breast tissue. Wavefront distortion causes image degradation. We have developed a novel signal processing technique, called Toward Inverse Filtering TIF, to compensate such distortion. In vitro one-way distortion compensation has shown that contrast resolution has been improved significantly with TIF. The second objective of this research is to develop a two-dimensional 2-D ultrasound array for the implementation of the compensation algorithms in two-way propagation. We have constructed two prototypes of 2-D ultrasound arrays operating at 1 Mhz and 5 Mhz, respectively. In addition to the originally proposed work, we have developed a novel imaging method which combines ultrasound and near infrared diffusive light techniques. Experiments with phantoms using one-dimensional and two-dimensional combined arrays have shown that lesion acoustic and optical parameters can be jointly evaluated and the target detection sensitivity and specificity can be improved significantly. Since lesion acoustic and optical properties are different, the combined method has a great potential to improve breast cancer detection.

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  • Medicine and Medical Research
  • Medical Facilities, Equipment and Supplies
  • Computer Programming and Software
  • Optics

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