Studies into Militarily Relevant Infectious Diseases of Interest to Both United States and Royal Thai Governments
Annual rept. 15 Oct 97-14 Oct 98
ARMED FORCES RESEARCH INST OF MEDICAL SCIENCES/ROYAL THAI ARMY MEDICAL COMPONENT BANGKOK
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Cooperative Agreement DAMD17-95-2-5001 was implemented 15 October 1994 to provide funding support for Royal Thai Army investigators at Armed Forces Research Institute of Medical Sciences AFRIMS engaged in research activities in collaboration with U.S. Army investigators. The principal focus of research under the agreement is directed to activities to prepare for development and testing of vaccines for prevention of HIV infection andor disease. During the report period, research activities were directed in 4 primary areas 1 continuing and expanding studies of natural history of HIV infectiondisease in Thais to define and establish endpoints for projected vaccine efficacy testing 2 cohort development studies attempting to define an appropriate populations for vaccine testing 3 conduction of phase 111 vaccine studies to determine safety and immunogenicity of potential HIV vaccines in Thais and 4 Active surveillance of RTA conscripts to determine the dynamics of HIV epidemic in Thailand. Other efforts under the Cooperative Agreement during the reporting period included 1 animal care and handling, including multiple small animal species and primate colony, in support of other ongoing research activities at AFRIMS, exclusive of HIV research and 2 site maintenance activities in support of research activities including glassware and utilities support.
- Medicine and Medical Research