Accession Number:

ADA357315

Title:

Fluorescence Lifetime Imaging for Breast Cancer Detection and Diagnosis

Descriptive Note:

Annual rept. 1 Jul 97-30 Jun 98

Corporate Author:

PURDUE RESEARCH FOUNDATION LAFAYETTE IN

Personal Author(s):

Report Date:

1998-07-01

Pagination or Media Count:

103.0

Abstract:

In this exploratory research program, the use of fluorescent contrast agents for detection and diagnosis of sub-surface diseased tissues is demonstrated. Using Newton-Raphson inversion techniques, we demonstrated the ability to map fluorescence lifetime and quantum efficiency from frequency-domain measurements of photon migration using synthetic data sets. Multi-pixel instrumentation for generation of actual data sets was constructed and is planned to validate the approach of fluorescence lifetime imaging of breast disease using optical contrast agents.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE