Preclinical Toxicology Studies for New Drugs and Vaccines.
Final rept. 15 Nov 91-15 Apr 98,
ILLINOIS UNIV AT CHICAGO CIRCLE
Pagination or Media Count:
This project evaluated the toxicity and safety of several drugs under development. During the contract, tasks conducted included mutagenicity tests developmental toxicity studies in rats and rabbits acute toxicity studies in rats and mice two, four and thirteen week toxicity studies in rats and dogs a six month toxicity study in rats fertilitylearly embryonic development studies, in rats a perinatal toxicity study in rats and a one year toxicity study in dogs. Drugs studied included WR242S ii Tartrate, WR2386OS Succinate, Halofantrine HCl, Pyridostigmine Bromide, WR6O26 Dihydrochioride, H1-6 Dichloride, WR26941O, Atropine, WR279396, and Ampicillin.
- Medicine and Medical Research