Accession Number:

ADA341389

Title:

Effects of Meditation-Based Stress Reduction in Younger Women with Breast Cancer.

Descriptive Note:

Annual rept. 30 Sep 96-29 Sep 97,

Corporate Author:

MASSACHUSETTS UNIV MEDICAL CENTER WORCESTER

Personal Author(s):

• Hebert, James R.

Report Date:

1997-10-01

Pagination or Media Count:

20.0

Abstract:

The Breast Research Initiative for Determining effective Skills for coping with Cancer BRIDGES consists of a prospective, randomized intervention trial with sixty women in each of three arms 1 the UMASS mindfulness meditation-based Stress Reduction and Relaxation Program SR RP 2 a nutrition education program NEP developed specifically for BRIDGES and 3 a usual care control group. The 180 women under age 65 with Stage I or Stage II breast cancer enrolling into this randomized trial are being evaluated for 1 psychological and behavioral indices of functions and coping 2 Quality of Life QOL measures 3 compliance with the interventions and with medical treatment regimes and 4 biochemicalimmunological measures consisting of cytokines and melatonin. Analyses will be conducted to test hypotheses related to the three specific aims of the study SRRP effect on QOL SR RI NEP effects on immune parameters and durabilitydecay of intervention-related effects. As of 30 September l997, the study had closely adhered to the Statement of Work agreed upon at the time the grant was awarded. 178 women were recruited and randomized into the study. Most subjects 90 who have been randomized and begun the study have been retained. All data have been collected as per protocol stipulations.

Descriptors:

• *STRESS(PHYSIOLOGY)
• *REDUCTION
• *BEHAVIOR
• *BREAST CANCER
• EDUCATION
• BIOCHEMISTRY
• RANDOM VARIABLES
• HYPOTHESES
• IMMUNOLOGY
• MEDICAL RESEARCH
• WOMEN
• INTERVENTION
• NUTRITION
• MEDICAL EXAMINATION
• LIVING STANDARDS
• MELATONIN

Subject Categories:

• Medicine and Medical Research
• Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE