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Effect of a Stress Reduction Intervention on Psycho- Immuno-Endocrine Parameters in Early Stage Breast Cancer.

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Annual rept. 30 Sep 96-29 Sep 97,

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This is a Career Development Award which provides salary support for research and training done under a separately- funded project, Grant Number DAMD17-94-J-4475 P.1. Dr. James R. Hebert, called the Breast Research initiative for Determining Effective Skills BRIDGES, which focuses on skills for coping with breast cancer, and consists of a prospective randomized intervention trial with women ages 65 or less, having stage 1 or 2 breast cancer, randomized to one of three arms 1 a modified form of the University of Massachusetts Medical Center mindfulness meditation- based Stress Reduction and Relaxation Program SRRP 2 a nutrition education program developed specifically for BRIDGES and 3 a usual-care control group. Outcome parameters are 1 psychological and behavioral indices of function and coping 2 quality of life measures 3 compliance with the interventions and medical treatment regimens and 4 immunologicalendocrinological measures consisting of cytokines and melatonin. Over the past year, I have been involved in the following aspects of the project recruitment, providing part of the SRRP intervention, writing manuscripts, serving on the Executive and Steering Committees, data analysis, and overseeing sample collection and analysis for the melatonin assays, quality control of the melatonin assay, first and second author of two book chapters related to the project, symposium presentation at the American Psychiatric Association annual meeting, and taking an introductory biostatistics course in the Dept. of Public Health.

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  • Medicine and Medical Research

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