Accession Number:

ADA339111

Title:

Use of Cytokines to Prevent Breast Cancer Growth and Progression

Descriptive Note:

Annual rept. 1 Aug 96-31 Jul 97

Corporate Author:

HENRY M JACKSON FOUNDATION ROCKVILLE MD

Personal Author(s):

Report Date:

1997-08-01

Pagination or Media Count:

24.0

Abstract:

The current project extends two sets of observations 1 Original work from our laboratories which showed that a cytoplasmic extract from transformed cells TKO interrupts the Stat1 signal transduction pathway of IFN-alphabeta 28 and 2 published work of others showing that human breast cancer cells can secrete PRL and thus might autonomously activate Stat 1 by tyrosine phosphorylation.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE