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The Effects of a Comprehensive Coping Strategy on Clinical Outcomes in Breast Cancer Bone Marrow Transplant Patients and Primary Caregiver.

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Annual rept. 1 Sep 96-31 Aug 97,

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The purpose of this 4 year study is to determine the effects of the Comprehensive Coping Strategy Program CCSP on clinical outcomes and quality of life in breast cancer patients and their primary caregivers. Specifically, the purpose of this study was to compare descriptions of pain, psychological distress, fatigue, and perceived health status and burden of care in breast cancer patients who received autologous bone marrow transplant ABMT and their primary caregivers PCGs and participated in a CCSP and ABMT breast cancer patients and their PCGs who did not receive the CCSP. A randomized controlled clinical trial design was used Thus far, 110 patients and 85 primary caregivers have entered the study. Data are presented on 100 patients and 83 PCGs. Fifty patients were randomly assigned to the CCSP treatment group and 45 to the control group. The ABMT was canceled in 5 patients before baseline data were collected but after the consent from had been signed. Data were collected 20 days before hospitalization baseline, during hospitalization 7 days after the ABMT, and again during the post hospitalization period which was 6 months to a year following the ABMT. The results showed trends that support the use of the CCSP in the reduction of psychological distress, improving the mental health status of the patient and increasing the number of hours of sleep. The CCSP group was able to avoid catastrophizing to a higher degree than the control group and reported a higher perception of health than the control group. Quality of life was improved in the psychologicalspiritual domain within the treatment group. The treatment group showed an overall improvement in QOL of 10 points p0.001. The control group showed a smaller 6.8 points improvement in QOL that was also significant 0.05.

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  • Anatomy and Physiology
  • Medicine and Medical Research

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