Stress and Immunity Breast Cancer Project
Annual rept 15 Aug 96-14 Aug 97
OHIO STATE UNIV RESEARCH FOUNDATION COLUMBUS
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Psychological research documents that the psychosocial burdens following breast cancer are notable in number, severity, and scope. A biobehavioral model of cancer stress and disease course has been proposed and provides a conceptual basis for the proposed research. We are testing the model with a clinical trial 235 women with stage II or III breast cancer who have been diagnosed and recently surgically treated are randomized between two conditions 1 assessment and intervention, or 2 assessment only control. In addition to documenting the quality of life benefits of a psychological intervention, this study provides an experimental test of the psychological and behavioral variables which may influence health outcomes directly. Further, we test specific mechanisms--alteration in immune and endocrine functions--to achieve beneficial health effects for women with breast cancer.
- Medicine and Medical Research