Steroid Hydroxylase Activities as Noninvasive Biomarkers of Toxicant Exposure and Effect
Final rept 1 Jun 94- 31 Oct 97
NORTH CAROLINA STATE UNIV AT RALEIGH CUTANEOUS PHARMACOLOGY AND TOXICOLOGY CENTER
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Biomarkers of chemical exposure and effect have substantial utility in chemical hazard and risk assessments. The overall goal of this research project was to test the hypothesis that changes in the metabolic elimination of the steroid hormone testosterone could serve as a non-invasive biomarker of toxicant exposure and effect in a variety of sentinel species and humans.
- Anatomy and Physiology
- Organic Chemistry