Accession Number:

ADA330711

Title:

A Genetic Approach to Mammalian Circadian Rhythms.

Descriptive Note:

Final rept. 1 May 94-30 Apr 97

Corporate Author:

PENNSYLVANIA UNIV PHILADELPHIA SCHOOL OF MEDICINE

Personal Author(s):

Report Date:

1995-01-01

Pagination or Media Count:

6.0

Abstract:

We have developed a routine procedure for random mutagenesis in the mouse and have demonstrated the feasibility of rapidly screening for aberrant behavioral parameters. We believe that this classical genetic approach, as well as the screening of progeny of mutagenized mice for altered sequence andor expression pattern prior to phenotypic analysis, will play an important role in the elucidation of the functional content of the mammalian genome.

Subject Categories:

  • Genetic Engineering and Molecular Biology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE