Cell-Matrix Interactions in Breast Carcinoma Invasion.
Annual rept. 15 Dec 95-14 Dec 96,
NEW YORK UNIV MEDICAL CENTER NY
Pagination or Media Count:
Transgenic mice carrying an activated form of the N-ras oncogene under the control of the Mammary Tumor Virus Long Terminal Repeat promoter developed mammary carcinomas with a high frequency during the first few months of their life. The alpha 6 beta 4 and, to a minor extent, the alpha 2 beta 1 integrin were found to be upregulated and diffusely distributed at the tumor cell surface in the primary lesions of these mice.
- Genetic Engineering and Molecular Biology
- Medicine and Medical Research