Spatial Distribution of the EGF Receptor in Regulation of Breast Epithelial Cell Growth and Organization.
Annual rept. 1 Sep 95-31 Aug 96,
UTAH UNIV SALT LAKE CITY
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An important goal of current breast cancer research is to develop an in vitro system that can define the mechanisms involved in the progression of human mammary epithelial cells HMEC towards a transformed phenotype. In this project, we have focused on an aspect of HMEC behavior that is likely to be involved in this progression, namely, the correct spatial sorting of growth factors and their receptors to discrete cellular locations.
- Genetic Engineering and Molecular Biology
- Medicine and Medical Research