Accession Number:

ADA327081

Title:

Spatial Distribution of the EGF Receptor in Regulation of Breast Epithelial Cell Growth and Organization.

Descriptive Note:

Annual rept. 1 Sep 95-31 Aug 96,

Corporate Author:

UTAH UNIV SALT LAKE CITY

Personal Author(s):

Report Date:

1997-03-01

Pagination or Media Count:

64.0

Abstract:

An important goal of current breast cancer research is to develop an in vitro system that can define the mechanisms involved in the progression of human mammary epithelial cells HMEC towards a transformed phenotype. In this project, we have focused on an aspect of HMEC behavior that is likely to be involved in this progression, namely, the correct spatial sorting of growth factors and their receptors to discrete cellular locations.

Subject Categories:

  • Biochemistry
  • Genetic Engineering and Molecular Biology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE