Mechanisms & Diagnostics of Ultrashort Pulse Laser Ocular Effects.
Final technical rept. 14 Apr 93-14 Apr 96,
MASSACHUSETTS INST OF TECH CAMBRIDGE RESEARCH LAB OF ELECTRONICS
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The objective of our program has been to investigate the mechanisms of short and ultrashort pulse laser retinal injury and to develop and apply new diagnostics for the assessment of retinal injury. A key focus of our effort during this program has been to develop and apply optical coherence tomography OCT to investigate the morphology of retinal laser injury. OCT is a new noninvasive optical diagnostic technique for micron scale cross sectional imaging, which can permit the noninvasive imaging of retinal microstructure in situ. Working in collaboration with investigators at Brooks AFB, we have applied OCT to study lesion structure, development, and healing response from laser retinal injury. An increased understanding of the mechanisms of laser retinal injury is relevant to the - - development of laser safety standards as well as the development and improvement of clinical laser therapies for ocular disease.
- Anatomy and Physiology
- Lasers and Masers