A Comprehensive Repository of Normal and Tumor Human Breast Tissue and Cells.
Annual rept. 1 Jul 95-30 Jun 96,
TEXAS UNIV AT DALLAS
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The development of breast cancer is likely to be a multi-step progressive process with several heritable alterations accumulated during the evolution to malignancy. In order to have surrogate endpoint markers to provide a means for early intervention, it is important to define the specific molecular alterations at each stage of this process. The study of such alterations should be greatly facilitated by having not only cells derived from breast tumors but also corresponding non-malignant breast cells of stromal and epithelial origin. We have successfully established a unique repository which contains cryopreserved and cultured cells from human breast tumor tissues, non-malignant breast epithelial and stromal cells and peripheral blood mononuclear cells.
- Anatomy and Physiology
- Medicine and Medical Research