Effect of a Stress Reduction Intervention on Psycho-Immuno-Endocrine Parameters in Early Stage Breast Cancer.
Annual rept. 30 Sep 94-29 Sep 95,
MASSACHUSETTS UNIV MEDICAL CENTER WORCESTER
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The Breast Research Initiative for Determining Effective Skills for coping with cancer BRIDGES consists of a prospective, randomized intervention trial with 60 women in each of three arms 1 the UMass mindfulness mediation-based Stress Reduction and Relaxation Program SRRP 2 a nutrition education program NEP developed specifically for BRIDGES and 3 a usual care control group. The 180 women under age 65 with Stage I or Stage II breast cancer enrolling into this randomized trial are being evaluated for 1 psychological and behavioral indices of function and coping 2 Quality of Life QOL measures, 3 compliance with the interventions and with medical treatment regimes, and 4 biochemicalimmunological measures consisting of cytokines and melatonin. Analyses will be conducted to test hypotheses related to the three specific aims of the study. SRRP effect on QOL SRRP NEP effects on immune parameters, and durabilitydecay of intervention-related effects. As of 30 Sep 19, the study had closely adhered to the SOW agreed upon at the time the grant was awarded. Recruitment has achieved and is maintaining targeted levels. All subjects who have begun the study have been retained. All data has been collected.
- *MEDICAL SERVICES
- *MAMMARY GLANDS
- *BREAST CANCER
- TEST AND EVALUATION
- RANDOM VARIABLES
- LIVING STANDARDS
- ENDOCRINE GLANDS
- Medicine and Medical Research
- Stress Physiology