Lymphedema: Incidence, Time Course and Etiology in Long-Term Survivors of Breast Cancer Cohort.
SLOAN-KETTERING INST FOR CANCER RESEARCH NEW YORK
Pagination or Media Count:
We are employing an existing extensive data base on a cohort of patients treated consecutively between October 1976 and June 1978 who were known to be free of recurrent breast cancer 10 years after diagnosis. The existing data base includes prospectively acquired information regarding clinical characteristics, intraoperative factors, pathological factors and the annually-updated medical and cancer history. The medical records have been reviewed for specific anatomical and surgical technique factors that were not part of the original data base but may be associated with lymphedema development. We are interviewing each survivor for a wide range of factors occurring since her cancer treatment, concerning upper extremity activity, function, injury, infection, as well as general activity and health status. We are collecting subjective measurements of lymphedema as well as objective self-reported measurements of arm circumferences. With this study design, we will calculate incidence and rate of lymphedema development. In a nested case-control analysis the women with lymphedema will be matched with women of the same age and stage without lymphedema in order to identify differences that may be predictive of lymphedema development.
- Medicine and Medical Research
- Escape, Rescue and Survival