Accession Number:

ADA301447

Title:

Positron Emitter I124 Iododeoxyuridine as a Tracer to Follow DNA Metabolism on Scans and in Tumor Samples in Advanced Breast Cancer.

Descriptive Note:

Annual rept.,

Corporate Author:

SLOAN-KETTERING INST FOR CANCER RESEARCH NEW YORK

Personal Author(s):

Report Date:

1995-09-01

Pagination or Media Count:

5.0

Abstract:

The objectives of this study are 1 to determine whether the biologic activity of locally advanced Stage III breast cancer as measured by 1241-iododeoxyuridine IUdR uptake on positron emission tomography PET scans pre and post chemotherapy can be correlated with the clinical response as determined by physical examination and conventional radiographic studies, 2 to demonstrate that incorporation of TUdR is into the DNA contained within the tumor and that it correlates with the subsequent tumor response and proliferative activity of the tumor, 3 to further assess the biologic activity of tumor sites and clinical response by using a program which fuses PET scan images on computed tomography CT scans, magnetic resonance imaging MRI or SPECT bone scans.

Subject Categories:

  • Medicine and Medical Research
  • Anatomy and Physiology
  • Acoustic Detection and Detectors

Distribution Statement:

APPROVED FOR PUBLIC RELEASE