Accession Number:

ADA300539

Title:

Progress Report for Contract Number N00014-93-C-0019. Quarterly Report Nomber 8. (Hawaii Biotechnology Group, Inc.).

Descriptive Note:

Quarterly rept. no. 8, 1 Oct-31 Dec 94.

Corporate Author:

HAWAII APPLIED RESEARCH INC HONOLULU

Personal Author(s):

Report Date:

1994-12-31

Pagination or Media Count:

28.0

Abstract:

1 The production of anti-ferret IgA antibodies. Status Immunization of rabbits and collection of sera completed. Mouse ascites successfully cross-adsorbed material sent to NMRI researchers in 1294. 2 The purification of lipopolysaccharide from Sbigella and Campylobacter species. Status Shigella sonnei and S. flexneri LPS delivered to NMRI researchers. Purification of C. jejuni LPS reinstated. Have collected 173mg of required a 200mg LPS. Production of remainder in progress. 3 The development of an enzyme immunoassay for the detection of enteroaggregative Escherichia coli heat-stable toxin. Status Initial recombinants provided by Navy unsatisfactory. Work suspended in 1093 due to contract funding reduction. Suitable recombinants still not available. 4 The production of monoclonal antibodies against strain-specific antigenic epitopes on Campylobacter coli flagella. Status Completed 3 fusions. No strain specific MAbs identified.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE