Identifying the Cognitive Decrements Caused by HIV.
Final rept. 1 Aug 90-31 Dec 94,
UNIVERSITY OF SOUTHERN CALIFORNIA LOS ANGELES INST OF SAFETY AND SYSTEMS MANA GEMENT
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This document summarizes the work conducted on this grant. One major experiment was conducted examining the effects of HIV on cognitive processes for a group of asymptomatic HIV homosexual and bisexual males, as defined using the Walter Reed Classification System. The HIV subjects were compared to a matched group of HIV- homosexual and bisexual males and to a second group of matched HIV- heterosexual males. Two types of cognitive assessment systems were used information processing and neuropsychological. A comparison of the two HIV- control groups revealed a number of significant differences on both the information processing and the neuropsychological instruments. Consequently, the group consisting of HIV- homosexual and bisexual males was selected as the appropriate control group. Few differences were found between the control group and the asymptomatic, HIV group. An interesting relation between performance on a classical vigilance task and self-reported recreational drug use was found. These data indicated that vigilance tasks may be useful as non-invasive drug screens.
- Medicine and Medical Research
- Anatomy and Physiology