Detection and Clinicopathologic Correlation of Human Immunodeficiency Virus (HIV-1) Nucleic Acids and Antigens in Reticuloendothelial and Central Nervous System Tissues, by Immunohistochemistry, in Situ Hybridization, and Polymerase Chain Reaction.
Annual rept. 1 Oct 93-30 Sep 94,
ARMED FORCES INST OF PATHOLOGY WASHINGTON DC
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The initial goals of this project are to collect autopsy tissues from HIV-positive asymptomatic drug addicts who die unexpectedly from drug overdoses. A wide sampling of autopsy tissue will be subjected to various techniques in identifying and localizing HIV-1. The viral burden, cellular sites of replication and progression of viral disease will be studied.
- Medicine and Medical Research