Support of the Center for Prostate Disease Research at Walter Reed Army Institute of Research.
Annual rept. 8 Feb-30 Sep 93,
UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD F EDWARD HEBERT SC HOOL OF MEDICINE
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The Center For Prostate Disease Research CPDR, a cooperative clinical and basic science research initiative focusing on prostate cancer and disease, began operations 14 September 1992 and this report summarizes the second year of operation. The CPDR is a research collaboration between the Uniformed Services University of the Health Sciences USUHS, Walter Reed Army Medical Center WRAMC Urology Program, and the Armed Forces Institute of Pathology AFIP Genito-urinary Pathology Department. Regarding clinical research, a comprehensive prostate cancer patient database has been established with prospective data gathering on all patients from WAAMC. A retrospective database of all patients treated at WAAMC since 1980 is also underway. A serum and tissue bank for all prostate cancer patients at WAAMC has also been established. Regarding basic research, a fully equipped molecular biology laboratory has been established at USUHS for the exclusive study of the molecular genetics and cellular markers in prostate cancer and disease. The full collaborative cooperation between clinicians, clinical researchers, and basic scientists within CPDR has already been productive. The group has reported a commonly mutated region in the Androgen Receptor AR gene in advanced prostate cancer. Work is ongoing to determine the clinical significance of this genetic alteration. The CPDR group is excited and enthusiastic to continue with the clinical and basic research study of prostate cancer and disease within the DoD health care system and university.
- Anatomy and Physiology
- Medicine and Medical Research