Accession Number:

ADA289094

Title:

Establishment of a Center for Environmental Medicine at the Medical College of Ohio.

Descriptive Note:

Final rept. 15 Sep 93-14 Sep 94,

Corporate Author:

MEDICAL COLL OF OHIO AT TOLEDO

Personal Author(s):

• Pereier, Michael A.
• Olson, Dan E.

Report Date:

1994-05-07

Pagination or Media Count:

100.0

Abstract:

The Center for Environmental Medicine has been established at the Medical College of Ohio, Toledo, Ohio with Dr Michael A. Pereira, Ph.D. as Director. The Center consists of two divisions, i.e. Molecular Toxicology and Respiratory Toxicology. The Molecular Toxicology Division has initiated studies to better understand the carcinogenic activity of compounds of interest to the U.S. Air Force. These studies have emphasized trichloroethylene, a major contaminant around Air Force bases. A letter of agreement with Wright-Patterson Air Force Base is being formalized so as to allow their collaboration. Studies that have been initiated include 1 demonstration of the tumor promoting activity of trichloroethylene in mouse liver 2 determination of the molecular mechanism for the tumor promoting activity of trichloroethylene and 3 determination of the biochemical molecular activity of trichloroethylene in mouse liver. The Respiratory Toxicology Division has initiated the following studies Program information has been obtained to determine the appropriate site, space needs, design criteria and project cost for a building to house the Center for Environmental Medicine.

Descriptors:

• *UNIVERSITIES
• *CARCINOGENS
• *TRICHLOROETHYLENE
• *TOXICOLOGY
• TOXIC HAZARDS
• BIOCHEMISTRY
• OHIO
• CONTAMINANTS
• MOLECULAR BIOLOGY
• AIR FORCE FACILITIES
• MICE
• HEALTH CARE FACILITIES
• MEDICAL RESEARCH

Subject Categories:

• Humanities and History
• Medicine and Medical Research
• Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE