Accession Number:

ADA285313

Title:

Arthropod-Borne Viral Infectious Associated with a Fever Outbreak in the Northern Province of Sudan

Descriptive Note:

Corporate Author:

NAVAL MEDICAL RESEARCH UNIT NO 3 CAIRO (EGYPT) DEPT OF MEDICAL ZOOLOGY

Report Date:

1994-01-01

Pagination or Media Count:

5.0

Abstract:

An outbreak of acute febrile illness occurred during August and September 1989 in the Northern Province of Sudan coinciding with a high population density of phlebotomine sandflies. An investigation was conducted to determine whether arboviruses were associated with human illness during this outbreak. Sera were obtained from 185 febrile individuals and tested for IgG and IgM antibody to selected arboviruses by enzyme immunoassay EIA. The prevalence of IgG antibody was 59 for West Nile WN, 53 for Sandfly Fever Sicilian SFS, 32 for Sandfly Fever Naples SFN, 39 for Yellow Fever YF, 24 for dengue-2 DEN-2, 23 for Rift Valley RVF, 12 for Chikungunya CHIK and 5 for Crimean-Congo Haemorrhagic Fever CCHF viruses. Antibody prevalences tended to increase with age for WN and YF viruses. Antibody rates were about the same for males and females for most of the viruses tested. The prevalence of IgM antibody to SFN was 24 and reciprocal 1gM titre exceeded 12 800 for some individuals suggesting that this virus was the cause of recent infection. The prevalence of IgM antibody for the other viruses did not exceed 5. The study indicated that several arboviruses were endemic and some of them may have caused human disease in the Northern Province of Sudan.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE