Neural Networks: Structure and Repair. Part 1. Ground Squirrel Visual System. Part 2. Formation, Maintenance and Plasticity of Synaptic Connections
Progress rept. 1993-1994,
PUERTO RICO UNIV SAN JUAN INST OF NEUROBIOLOGY
Pagination or Media Count:
This project uses the visual system of squirrels, with special emphasis on the retina, to study the normal organization of neural networks. Over the past year we have added to our knowledge of the organization of the retinal ganglion cell layer 1 We have determined that only 50 of the cells in the ganglion cell layer are retinal ganglion cells. 2 Retinal ganglion cells projecting to the superior colliculus have been identified using Cholera Toxin subunit B CTB as a retrograde tracer. The ZIDAS and Neurolucida image analysis systems have been used to characterize the dendritic tree of the medium-sized cells from this group. Differences in the organization of the dendritic tree suggest that these cells comprise more than one subpopulation. 3 Experiments to determine whether retinal ganglion cells project to more than one retinal projection target have revealed that ganglion cells in this species do not project bilaterally to any significant degree.
- Anatomy and Physiology